The Ministry is charged with the following responsibilities:
Formation and implementation of Government policy on Science and Technology.
Production and Sustenance of indigenous science and technology.
Installation and maintenance of telecommunication equipment in the State.
Establishment of a Technology data bank for the State.
Collation of valuable inventions and research, and, development results.
Liaison with research and industrial organisations for joint research activities.
Development of Science and Technology Park.
Creating a technology-driven economy.
Enlightenment of industrialists on application of modern technologies in their development strategies.
Liaison with the Federal Ministry of Science and Technology and similar National/International Agencies.
Relating with Akwa Ibom State University.
Management of the e-library.
Development, Installation and Maintenance of ICT infrastructure and management of personnel.